 |
|
|
Publications including work performed on the Genomics Platform
 |
|
S.I. Anghel, E. Bedu, C. Delucinge Vivier, P. Descombes, B. Desvergne and W. Wahli (2007).
Adipose tissue integrity as a prerequisite for systemic energy balance: a critical role for peroxisome proliferator-activated receptor gamma.
Journal of Biological Chemistry 282, 29946-29957.
|
| |
|
|
A. Bianchi and D. Shore (2007).
Early replication of short telomeres in budding yeast.
Cell 128, 1051-1062.
|
| |
|
|
C.R. Cederroth, O. Schaad, P. Descombes, P. Chambon, J.-D. Vassalli and S. Nef (2007).
Estrogen receptor α is a major contributor to estrogen-mediated fetal testis dysgenesis and cryptorchidism.
Endocrinology 148, 5507-5519.
|
| |
|
|
C.R. Cederroth, M. Vinciguerra, F. Kühne, R. Madani, D.R. Doerge, T.J. Visser, M. Foti, F. Rohner-Jeanrenaud, J.-D. Vassalli and S. Nef (2007).
A phytoestrogen-rich diet increases energy expenditure and decreases adiposity in mice.
Environmental Health Perspectives 115, 1467-1473.
|
| |
|
|
A. De Gottardi, M. Vinciguerra, A. Sgroi, M. Moukil, F. Ravier-Dall’Antonia, V. Pazienza, P. Pugnale, M. Foti and A. Hadengue (2007).
Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes.
Laboratory Investigation 87, 792-806.
|
| |
|
|
J. Fellay, K.V. Shianna, D. Ge, S. Colombo, B. Ledergerber, M. Weale, K. Zhang, C. Gumbs, A. Castagna, A. Cossarizza, A. Cozzi-Lepri, A. De Luca, P. Easterbrook, P. Francioli, S. Mallal, J. Martinez-Picado, J.M. Miro, N. Obel,
J.P. Smith, J. Wyniger, P. Descombes, S.E. Antonarakis, N.L. Letvin, A.J. McMichael, B.F. Haynes, A. Telenti and D.B. Goldstein (2007).
A whole-genome association study of major determinants for host control of HIV-1.
Science 317, 944-947.
|
| |
|
|
G. Gavazzi, C. Deffert, C. Trocme, M. Schäppi, F.R. Herrmann and K.-H. Krause (2007).
NOX1 deficiency protects from aortic dissection in response to angiotensin II.
Hypertension 50, 189-196.
|
| |
|
|
D.A. Glauser, T. Brun, B.R. Gauthier and W. Schlegel (2007).
Transcriptional response of pancreatic beta cells to metabolic stimulation: large scale identification of immediate-early and secondary response genes.
BMC Molecular Biology 8, Art. 54.
|
| |
|
|
B. Kornmann, O. Schaad, H. Bujard, J.S. Takahashi and U. Schibler (2007).
System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock.
PLoS Biology 5, 179-189.
|
| |
|
|
C. Ody, S. Jungblut-Ruault, D. Cossali, M. Barnet, M. Aurrand-Lions, B.A. Imhof and T. Matthes (2007).
Junctional adhesion molecule C (JAM-C) distinguishes CD27+ germinal center B lymphocytes from non-germinal center cells and constitutes a new diagnostic tool for B-cell malignancies.
Leukemia 21, 1285-1293.
|
| |
|
|
P. Prandini, S. Deutsch, R. Lyle, M. Gagnebin, C. Delucinge Vivier, M. Delorenzi, C. Gehrig, P. Descombes, S. Sherman, F. Dagna Bricarelli, C. Baldo, A. Novelli, B. Dallapiccola and S.E. Antonarakis (2007).
Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance.
American Journal of Human Genetics 81, 252-263.
|
| |
|
|
L. Serrander, L. Cartier, K. Bedard, B. Banfi, B. Lardy, O. Plastre,
A. Sienkiewicz, L. Forro, W. Schlegel and K.-H. Krause (2007).
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.
Biochemical Journal 406, 105-114.
|
| |
|
|
S.-J. Zhang, M.N. Steijaert, D. Lau, G. Schütz, C. Delucinge-Vivier, P. Descombes and H. Bading (2007).
Decoding NMDA receptor signaling: identification of genomic programs specifying neuronal survival and death.
Neuron 53, 549-562.
|
| |
|
|
L. Cartier, T. Laforge, A. Feki, S. Arnaudeau, M. Dubois-Dauphin and K.-H. Krause (2006).
Pax6-induced alteration of cell fate: shape changes, expression of neuronal α tubulin, postmitotic phenotype, and cell migration.
Journal of Neurobiology 66, 421-436.
|
| |
|
|
F. Cléard, Y. Moshkin, F. Karch and R.K. Maeda (2006).
Probing long-distance regulatory interactions in the Drosophila melanogaster bithorax complex using Dam identification.
Nature Genetics 38, 931-935.
|
| |
|
|
S. Fineschi, W. Reith, P.A. Guerne, J.-M. Dayer and C. Chizzolini (2006).
Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts.
FASEB Journal 20, 562-564.
|
| |
|
|
F. Gachon, F. Fleury Olela, O. Schaad, P. Descombes and U. Schibler (2006).
The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification.
Cell Metabolism 4, 25-36.
|
| |
|
|
G. Gavazzi, B. Banfi, C. Deffert, L. Fiette, M. Schappi, F. Herrmann and K.-H. Krause (2006).
Decreased blood pressure in NOX1-deficient mice.
FEBS Letters 580, 497-504.
|
| |
|
|
L. Gurcel, L. Abrami, S. Girardin, J. Tschopp and F.G. Van der Goot (2006).
Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival.
Cell 126, 1135-1145.
|
| |
|
|
L. Hermida, O. Schaad, P. Demougin, P. Descombes and M. Primig (2006).
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation.
BMC Bioinformatics 7, 190-199.
|
| |
|
|
F. Homo-Delarche, S. Calderari, J.-C. Irminger, M.-N. Gangnerau, J. Coulaud, K. Rickenbach, M. Dolz, P. Halban, B. Portha and P. Serradas (2006).
Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat.
Diabetes 55, 1625-1633.
|
| |
|
|
O. Menzel, M. Migliaccio, D.R. Goldstein, S. Dahoun, M. Delorenzi and N. Rufer (2006).
Mechanisms regulating the proliferative potential of human CD8+ T lymphocytes overexpressing telomerase.
Journal of Immunology 177, 3657-3668.
|
| |
|
|
M. Pihlgren, M. Friedli, C. Tougne, A.-F. Rochat, P.-H. Lambert and C.-A. Siegrist (2006).
Reduced ability of neonatal and early-life bone marrow stromal cells to support plasmablast survival.
Journal of Immunology 176, 165-172.
|
| |
|
|
D. Roppolo, V. Ribaud, V. Pauli Jungo, C. Lüscher and I. Rodriguez (2006).
Projection of the Grüneberg ganglion to the mouse olfactory bulb.
European Journal of Neuroscience 23, 2887-2894.
|
| |
|
|
M. Schmid, G. Arib, C. Laemmli, J. Nishikawa, T. Durussel and U.K. Laemmli (2006).
Nup-PI: the nucleopore-promoter interaction of genes in yeast.
Molecular Cell 21, 379-391.
|
| |
|
|
A. Taddei, G. Van Houwe, F. Hediger, V. Kalck, F. Cubizolles, H. Schober and S.M. Gasser (2006).
Nuclear pore association confers optimal expression levels for an inducible yeast gene.
Nature 441, 774-778.
|
| |
|
|
C. Theander-Carrillo, P. Wiedmer, P. Cettour-Rose, R. Nogueiras, D. Perez-Tilve, P. Pfluger, T.R. Castaneda, P. Muzzin, A. Schürmann, I. Szanto, M.H. Tschöp and F. Rohner-Jeanrenaud (2006).
Ghrelin action in the brain controls adipocyte metabolism.
Journal of Clinical Investigation 116, 1983-1993.
|
| |
|
|
J. Cobb and D. Duboule (2005).
Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia.
Development 132, 3055-3067.
|
| |
|
|
T. Egener, E. Roulet, M. Zehnder, P. Bucher and N. Mermod (2005).
Proof of concept for microarray-based detection of DNA-binding oncogenes in cell extracts.
Nucleic Acids Research 33, e79.
|
| |
|
|
P. Farmer, H. Bonnefoi, V. Becette, M. Tubiana-Hulin, P. Fumoleau, D. Larsimont, G. MacGrogan, J. Bergh, D. Cameron, D. Goldstein, S. Duss, A.-L. Nicoulaz, C. Brisken, M. Fiche, M. Delorenzi and R. Iggo (2005).
Identification of molecular apocrine breast tumours by microarray analysis.
Oncogene 24, 4660-4671.
|
| |
|
|
S. Güimil, H.-S. Chang, T. Zhu, A. Sesma, A. Osbourn, C. Roux, V. Ioannidis, E.J. Oakeley, M. Docquier, P. Descombes, S.P. Briggs and U. Paszkowski (2005).
Comparative transcriptomics of rice reveals an ancient pattern of response to microbial colonization.
PNAS 102, 8066-8070.
|
| |
|
|
N. Lin-Marq, C. Borel and S.E. Antonarakis (2005).
Peutz-Jeghers LKB1 mutants fail to activate GSK-3ß, preventing it from inhibiting Wnt signaling.
Molecular Genetics and Genomics 273, 184-196.
|
| |
|
|
S. Nef, O. Schaad, N.R. Stallings, C.R. Cederroth, J-L. Pitetti, G. Schaer, S. Malki, M. Dubois-Dauphin, B. Boizet-Bonhoure, P. Descombes, K.L. Parker and J.-D. Vassalli (2005).
Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development.
Developmental Biology 287, 361-377.
|
| |
|
|
F.E. Perrin, G. Boisset, M. Docquier, O. Schaad, P. Descombes and A.C. Kato (2005).
No widespread induction of cell death genes occurs in pure motoneurons in an amyotrophic lateral sclerosis mouse model.
Human Molecular Genetics 14, 3309-3320.
|
| |
|
|
F. Gachon, P. Fonjallaz, F. Damiola, P. Gos, T. Kodama, J. Zakany, D. Duboule, B. Petit, M. Tafti and U. Schibler (2004).
The loss of circadian PAR bZip transcription factors results in epilepsy.
Genes & Development 18, 1397-1412.
|
| |
|
|
B.R. Gauthier, T. Brun, E.J. Sarret, H. Ishihara, O. Schaad, P. Descombes and C.B. Wollheim (2004).
Oligonucleotide microarray analysis reveals PDX1 as an essential regulator of mitochondrial metabolism in rat islets.
Journal of Biological Chemistry 279, 31121-31130.
|
| |
|
|
R. Lyle, C. Gehrig, C. Neergaard-Henrichsen, S. Deutsch and S.E. Antonarakis (2004).
Gene expression from the aneuploid chromosome in a trisomy mouse model of Down syndrome.
Genome Research 14, 1268-1274.
|
| |
|
|
V. Ossipow, F. Pellissier, O. Schaad and M. Ballivet (2004).
Gene expression analysis of the critical period in the visual cortex.
Molecular and Cellular Neuroscience 27, 70-83.
|
| |
|
|
S.B. Schawalder, M. Kabani, I. Howald, U. Choudhury, M. Werner and D. Shore (2004).
Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1.
Nature 432, 1058-1061.
|
| |
|
|
U. Schlecht, P. Demougin, R. Koch, L. Hermida, C. Wiederkehr, P. Descombes, C. Pineau, B. Jégou and M. Primig (2004).
Expression profiling of mammalian male meiosis and gametogenesis identifies novel candidate genes for roles in the regulation of fertility.
Molecular Biology of the Cell 15, 1031-1043.
|
| |
|
|
S. Nef, S. Verma-Kurvari, J. Merenmies, J.-D. Vassalli, A. Efstratiadis, D. Accili and L.F. Parada (2003).
Testis determination requires insulin receptor family function in mice.
Nature 426, 291-295.
|
| |
|
|
M. Tafti, B. Petit, D. Chollet, E. Neidhart, F. de Bilbao, J.Z. Kiss, P.A. Wood and P. Franken (2003).
Deficiency in short-chain fatty acid beta-oxidation affects theta oscillations during sleep.
Nature Genetics 34, 320-325.
|
|
|
|
|
