The Metabolic Evaluation Facility (MEF), hosted in Lausanne, results from a joint effort of NCCR members, the Center for Integrative Genomics of the University of Lausanne, and the Lausanne University Hospital (CHUV). The mission of the MEF is to provide the NCCR and lemanic research community with a wide repertoire of state-of-the-art, standardized techniques to analyze the metabolic status of mice models of complex human disorders.